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KMID : 0367419970400030403
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Journal of Korean Pediatric Society
1997 Volume.40 No. 3 p.403 ~ p.407
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Three Cases of Cardiac Arrythmias Associated with Intravenous Methylprednisolone Pulse Therapy
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이준호
허준/신명동/진동규/하일수/정해일/노정일/최용
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Abstract
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Methylprednisolone(MP) is administered by means of intravenous pulse therapy especially in the patients with focal segmental glomerulosclerosis(FSGS). There have been reports of its complications in a few increasing frequency. We experienced three cases of cardiaccomplications during intravenous pulsetherapy.Therewere onecaseof2¡ÆA-V block(Mobitztype I) and two cases of bradycardia and hypotension. In the former,2¡ÆA-V block in the first case deveoloped 45 hours after MP infusion and subsided subsequently but reappeared athis EKG checked after 4 months. All of these complications resolved spontaneously. We should be awared of the fact that arrythmia resulting from MP infusion can be fetal.Therefore when IMPT are attempted, we should keep in mind of emergency life-saving preparations at bedside.
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KEYWORD
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Methy 1 predni solone, Arrhythmia
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